Molecular Toxicology

Aim of the course

This module is focused on understanding mechanisms of toxicity at the molecular level.

This intensive, week-long course is designed to provide participants with cutting-edge insights into the principles, tools, and applications of molecular toxicology, with a particular focus on human-relevant in vitro systems (aka New Approach Methodologies).

  • Mechanisms of cellular toxicity and stress response pathways
  • Human cell-based models: from primary cells to organ-on-a-chip technologies
  • Xenobiotic metabolism and transporters in ADME/T
  • Functional assays for toxicity and mitochondrial health
  • The promise and pitfalls of current New Approach Methodologies (NAMs)

Coordinator(s): Prof. dr. Paul Jennings and dr. Maxime Culot

Examination
There will be a written exam at the end of the week.

Information

The course will be held hybrid with three days online and two days onsite. For those who are not able to travel to Amsterdam, there is the opportunity to follow the full course online.

Please note that the course can be cancelled up to one month before its starting date, when the number of applications is below the minimum required. For general inquiries please contact the PET Office.

Mutagenesis and Carcinogenesis
Medical and Forensic Toxicology